What is the meaning of Revelation 16:2?

* The two F.O.G. Bibles & Commentary below are currently a work in progress.

So the first angel went and poured out his bowl on the earth, and loathsome, malignant sores broke out on those who had the mark of the beast and worshiped its image.

Berean Standard Bible (BSB)

The first went, and poured out his bowl into the earth, and it became a harmful and evil sore on the people who had the mark of the beast, and who worshiped his image.

World English Bible (WEB)

And{G2532} the first{G4413} went{G565}{(G5627)}, and{G2532} poured out{G1632}{(G5656)} his{G846} vial{G5357} upon{G1909} the earth{G1093}; and{G2532} there fell{G1096}{(G5633)} a noisome{G2556} and{G2532} grievous{G4190} sore{G1668} upon{G1519} the men{G444} which{G3588} had{G2192}{(G5723)} the mark{G5480} of the beast{G2342}, and{G2532} upon them which worshipped{G4352}{(G5723)} his{G846} image{G1504}.

Strong's King James

(2) The first went away and poured out his bowl into the land and it became a wretchedly evil sore on mankind who had the beast's mark and those worshipping his image.

The F.O.G*

[2] The first messenger stepped forward and poured out his bowl onto the land. Immediately, painful and malignant sores erupted on those who had aligned themselves with the beast's system and worshiped its image—their external afflictions reflecting their internal corruption.

The F.O.G Paraphrase

and the first did go away, and did pour out his vial upon the land, and there came a sore—bad and grievous—to men, those having the mark of the beast, and those bowing to his image.

Young's Literal Translation